The use of vitamin D in chronic kidney disease

Simona Barbuto 1, Sandro Giannini 2, Giuseppe Cianciolo 1

1Nephrology, Dialysis and Transplantation Unit, IRCCS - Bologna University Hospital, Alma Mater Studiorum University of Bologna; 2Medical Clinic, Department of Medicine, University of Padua

DOI 10.30455/2611-2876-2023-4e

The term “vitamin D” denotes a group of steroid, fat-soluble compounds that are essential for the regulation of calcium and phosphorous metabolism, mediated mainly through intestinal absorption. The two most important isoforms, referred to cumulatively as “native vitamin D”, are ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3). Ergocalciferol, which is only synthesised by plants and fungi, is introduced through the diet, whereas cholecalciferol, on the other hand, is both exogenously and endogenously synthesised and is derived from the photolysis of 7-dehydrocholesterol, mediated by UVB radiation affecting the skin.




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